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Three-Dimensional RNA Structure of the Major HIV-1 Packaging Signal Region

HIV-1 genomic RNA has a noncoding 5′ region containing sequential conserved structural motifs that control many parts of the life cycle. Very limited data exist on their three-dimensional (3D) conformation and, hence, how they work structurally. To assemble a working model, we experimentally reasses...

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Detalles Bibliográficos
Autores principales: Stephenson, James D., Li, Haitao, Kenyon, Julia C., Symmons, Martyn, Klenerman, Dave, Lever, Andrew M.L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3690526/
https://www.ncbi.nlm.nih.gov/pubmed/23685210
http://dx.doi.org/10.1016/j.str.2013.04.008