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Polarized Cdc42 activation promotes polar body protrusion and asymmetric division in mouse oocytes

Asymmetric meiotic divisions in mammalian oocytes rely on the eccentric positioning of the spindle and the remodeling of the overlying cortex, resulting in the formation of small polar bodies. The mechanism of this cortical polarization, exemplified by the formation of a thick F-actin cap, is poorly...

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Detalles Bibliográficos
Autores principales: Dehapiot, Benoit, Carrière, Virginie, Carroll, John, Halet, Guillaume
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3690527/
https://www.ncbi.nlm.nih.gov/pubmed/23384564
http://dx.doi.org/10.1016/j.ydbio.2013.01.029