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Polarized Cdc42 activation promotes polar body protrusion and asymmetric division in mouse oocytes
Asymmetric meiotic divisions in mammalian oocytes rely on the eccentric positioning of the spindle and the remodeling of the overlying cortex, resulting in the formation of small polar bodies. The mechanism of this cortical polarization, exemplified by the formation of a thick F-actin cap, is poorly...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3690527/ https://www.ncbi.nlm.nih.gov/pubmed/23384564 http://dx.doi.org/10.1016/j.ydbio.2013.01.029 |