Insights into Degron Recognition by APC/C Coactivators from the Structure of an Acm1-Cdh1 Complex

The anaphase-promoting complex/cyclosome (APC/C) regulates sister chromatid segregation and the exit from mitosis. Selection of most APC/C substrates is controlled by coactivator subunits (either Cdc20 or Cdh1) that interact with substrate destruction motifs—predominantly the destruction (D) box and...

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Detalles Bibliográficos
Autores principales: He, Jun, Chao, William C.H., Zhang, Ziguo, Yang, Jing, Cronin, Nora, Barford, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3690534/
https://www.ncbi.nlm.nih.gov/pubmed/23707760
http://dx.doi.org/10.1016/j.molcel.2013.04.024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3690534/
https://www.ncbi.nlm.nih.gov/pubmed/23707760
http://dx.doi.org/10.1016/j.molcel.2013.04.024

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