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Evolutionary conflicts between viruses and restriction factors shape immunity

Host restriction factors are potent, widely expressed intracellular blocks to viral replication that are an important component of the innate immune response to viral infection. However, viruses have evolved mechanisms that antagonize restriction factors. Through evolutionary pressure for both host...

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Detalles Bibliográficos
Autores principales: Duggal, Nisha K., Emerman, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3690816/
https://www.ncbi.nlm.nih.gov/pubmed/22976433
http://dx.doi.org/10.1038/nri3295