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Directed Differentiation of Human Embryonic Stem Cells into Corticofugal Neurons Uncovers Heterogeneous Fezf2-Expressing Subpopulations

Understanding how neuronal diversity is achieved within the cerebral cortex remains a major challenge in neuroscience. The advent of human embryonic stem cells (hESCs) as a model system provides a unique opportunity to study human corticogenesis in vitro and to identify the mechanisms that promote n...

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Detalles Bibliográficos
Autores principales: Kmet, Muriel, Guo, Chao, Edmondson, Carina, Chen, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691138/
https://www.ncbi.nlm.nih.gov/pubmed/23826257
http://dx.doi.org/10.1371/journal.pone.0067292