Down-Regulation of 11β-Hydroxysteroid Dehydrogenase Type 2 by Bortezomib Sensitizes Jurkat Leukemia T Cells against Glucocorticoid-Induced Apoptosis

11β-hydroxysteroid dehydrogenases type 2 (11β-HSD2), a key regulator for pre-receptor metabolism of glucocorticoids (GCs) by converting active GC, cortisol, to inactive cortisone, has been shown to be present in a variety of tumors. But its expression and roles have rarely been discussed in hematolo...

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Detalles Bibliográficos
Autores principales: Tao, Yi, Gao, Lu, Wu, Xiaosong, Wang, Hongmei, Yang, Guang, Zhan, Fenghuang, Shi, Jumei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691151/
https://www.ncbi.nlm.nih.gov/pubmed/23826195
http://dx.doi.org/10.1371/journal.pone.0067067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691151/
https://www.ncbi.nlm.nih.gov/pubmed/23826195
http://dx.doi.org/10.1371/journal.pone.0067067

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