Lipoxin A(4)-Induced Heme Oxygenase-1 Protects Cardiomyocytes against Hypoxia/Reoxygenation Injury via p38 MAPK Activation and Nrf2/ARE Complex

OBJECTIVE: To investigate whether lipoxin A(4) (LXA(4)) increases expression of heme oxygenase-1(HO-1) in cardiomyocytes, whether LXA(4)-induced HO-1 protects cardiomyocytes against hypoxia/reoxygenation (H/R) injury, and what are the mechanisms involved in the LXA(4)-induced HO-1 induction. METHODS...

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Detalles Bibliográficos
Autores principales: Chen, Xiao-Qing, Wu, Sheng-Hua, Zhou, Yu, Tang, Yan-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691153/
https://www.ncbi.nlm.nih.gov/pubmed/23826208
http://dx.doi.org/10.1371/journal.pone.0067120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691153/
https://www.ncbi.nlm.nih.gov/pubmed/23826208
http://dx.doi.org/10.1371/journal.pone.0067120

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