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In Intact Islets Interstitial GABA Activates GABA(A) Receptors That Generate Tonic Currents in α-Cells
In the rat islets γ-aminobutyric acid (GABA) is produced by the β-cells and, at least, the α-cells express the GABA(A) receptors (GABA(A) channels). In this study, we examined in intact islets if the interstitial GABA activated the GABA(A) receptors. We used the patch-clamp technique to record whole...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691163/ https://www.ncbi.nlm.nih.gov/pubmed/23826240 http://dx.doi.org/10.1371/journal.pone.0067228 |