Modulation of Hepatitis C Virus RNA Accumulation and Translation by DDX6 and miR-122 Are Mediated by Separate Mechanisms

DDX6 and other P-body proteins are required for efficient replication of Hepatitis C Virus (HCV) by unknown mechanisms. DDX6 has been implicated in miRNA induced gene silencing, and since efficient HCV replication and translation relies on the cellular microRNA, miR-122, we hypothesized that DDX6 ha...

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Detalles Bibliográficos
Autores principales: Huys, Adam, Thibault, Patricia A., Wilson, Joyce A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691176/
https://www.ncbi.nlm.nih.gov/pubmed/23826300
http://dx.doi.org/10.1371/journal.pone.0067437

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691176/
https://www.ncbi.nlm.nih.gov/pubmed/23826300
http://dx.doi.org/10.1371/journal.pone.0067437

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