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Metal Binding Is Critical for the Folding and Function of Laminin Binding Protein, Lmb of Streptococcus agalactiae

Lmb is a 34 kDa laminin binding surface adhesin of Streptococcus agalactiae. The structure of Lmb reported by us recently has shown that it consists of a metal binding crevice, in which a zinc ion is coordinated to three highly conserved histidines. To elucidate the structural and functional signifi...

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Detalles Bibliográficos
Autores principales: Ragunathan, Preethi, Sridaran, Divya, Weigel, Anja, Shabayek, Sarah, Spellerberg, Barbara, Ponnuraj, Karthe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691195/
https://www.ncbi.nlm.nih.gov/pubmed/23826314
http://dx.doi.org/10.1371/journal.pone.0067517