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Response Prediction to Neoadjuvant Chemotherapy: Comparison between Pre-Therapeutic Gene Expression Profiles and In Vitro Chemosensitivity Assay

Although the use of (neo-)adjuvant chemotherapy in breast cancer patients has resulted in improved outcome, not all patients benefit equally. We have evaluated the utility of an in vitro chemosensitivity assay in predicting response to neoadjuvant chemotherapy. Pre-therapeutic biopsies were obtained...

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Detalles Bibliográficos
Autores principales: Singer, Christian F., Klinglmüller, Florian, Stratmann, Rembert, Staudigl, Christine, Fink-Retter, Anneliese, Gschwantler, Daphne, Helmy, Samir, Pfeiler, Georg, Dressler, Anne Catharina, Sartori, Christian, Bilban, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691196/
https://www.ncbi.nlm.nih.gov/pubmed/23826101
http://dx.doi.org/10.1371/journal.pone.0066573