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Mutational Analysis of Hedgehog Signaling Pathway Genes in Human Malignant Mesothelioma

BACKGROUND: The Hedgehog (HH) signaling pathway is critical for embryonic development and adult homeostasis. Recent studies have identified regulatory roles for this pathway in certain cancers with mutations in the HH pathway genes. The extent to which mutations of the HH pathway genes are involved...

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Detalles Bibliográficos
Autores principales: Lim, Chuan Bian, Prêle, Cecilia M., Cheah, Hui Min, Cheng, Yuen Yee, Klebe, Sonja, Reid, Glen, Watkins, D. Neil, Baltic, Svetlana, Thompson, Philip J., Mutsaers, Steven E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691204/
https://www.ncbi.nlm.nih.gov/pubmed/23826113
http://dx.doi.org/10.1371/journal.pone.0066685