Inferring Epitopes of a Polymorphic Antigen Amidst Broadly Cross-Reactive Antibodies Using Protein Microarrays: A Study of OspC Proteins of Borrelia burgdorferi

Epitope mapping studies aim to identify the binding sites of antibody-antigen interactions to enhance the development of vaccines, diagnostics and immunotherapeutic compounds. However, mapping is a laborious process employing time- and resource-consuming ‘wet bench’ techniques or epitope prediction...

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Detalles Bibliográficos
Autores principales: Baum, Elisabeth, Randall, Arlo Z., Zeller, Michael, Barbour, Alan G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691210/
https://www.ncbi.nlm.nih.gov/pubmed/23826301
http://dx.doi.org/10.1371/journal.pone.0067445

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691210/
https://www.ncbi.nlm.nih.gov/pubmed/23826301
http://dx.doi.org/10.1371/journal.pone.0067445

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