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Tumorspheres but Not Adherent Cells Derived from Retinoblastoma Tumors Are of Malignant Origin

Verification that cell lines used for cancer research are derived from malignant cells in primary tumors is imperative to avoid invalidation of study results. Retinoblastoma is a childhood ocular tumor that develops from loss of functional retinoblastoma protein (pRb) as a result of genetic or epige...

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Detalles Bibliográficos
Autores principales: Bond, Wesley S., Akinfenwa, Patricia Y., Perlaky, Laszlo, Hurwitz, Mary Y., Hurwitz, Richard L., Chévez-Barrios, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691222/
https://www.ncbi.nlm.nih.gov/pubmed/23826078
http://dx.doi.org/10.1371/journal.pone.0063519