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Tumorspheres but Not Adherent Cells Derived from Retinoblastoma Tumors Are of Malignant Origin
Verification that cell lines used for cancer research are derived from malignant cells in primary tumors is imperative to avoid invalidation of study results. Retinoblastoma is a childhood ocular tumor that develops from loss of functional retinoblastoma protein (pRb) as a result of genetic or epige...
Autores principales: | Bond, Wesley S., Akinfenwa, Patricia Y., Perlaky, Laszlo, Hurwitz, Mary Y., Hurwitz, Richard L., Chévez-Barrios, Patricia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691222/ https://www.ncbi.nlm.nih.gov/pubmed/23826078 http://dx.doi.org/10.1371/journal.pone.0063519 |
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