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Discovery and Validation of a Prostate Cancer Genomic Classifier that Predicts Early Metastasis Following Radical Prostatectomy

PURPOSE: Clinicopathologic features and biochemical recurrence are sensitive, but not specific, predictors of metastatic disease and lethal prostate cancer. We hypothesize that a genomic expression signature detected in the primary tumor represents true biological potential of aggressive disease and...

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Detalles Bibliográficos
Autores principales: Erho, Nicholas, Crisan, Anamaria, Vergara, Ismael A., Mitra, Anirban P., Ghadessi, Mercedeh, Buerki, Christine, Bergstralh, Eric J., Kollmeyer, Thomas, Fink, Stephanie, Haddad, Zaid, Zimmermann, Benedikt, Sierocinski, Thomas, Ballman, Karla V., Triche, Timothy J., Black, Peter C., Karnes, R. Jeffrey, Klee, George, Davicioni, Elai, Jenkins, Robert B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691249/
https://www.ncbi.nlm.nih.gov/pubmed/23826159
http://dx.doi.org/10.1371/journal.pone.0066855