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The Combination of SMAD4 Expression and Histological Grade of Dysplasia Is a Better Predictor for the Malignant Transformation of Oral Leukoplakia

Oral leukoplakia (OL) is the most common premalignancy in the oral cavity and can progress to oral squamous cell carcinoma (OSCC). SMAD4 is a tumor suppressor implicated in multiple cancer types including OSCC. To assess the role of SMAD4 in oral leukoplakia malignant transformation, the authors inv...

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Detalles Bibliográficos
Autores principales: Xia, Rong-Hui, Song, Xiao-Meng, Wang, Xiao-Jing, Li, Jiang, Mao, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691281/
https://www.ncbi.nlm.nih.gov/pubmed/23826135
http://dx.doi.org/10.1371/journal.pone.0066794