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MicroRNA-21 Knockout Improve the Survival Rate in DSS Induced Fatal Colitis through Protecting against Inflammation and Tissue Injury

BACKGROUND: MicroRNA-21 (miR-21) is overexpressed in most inflammatory diseases, but its physiological role in gut inflammation and tissue injury is poorly understood. The goal of this work is to understand the role of miR-21 in colitis and damage progression of intestine in a genetically modified m...

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Detalles Bibliográficos
Autores principales: Shi, Chenzhang, Liang, Yong, Yang, Jun, Xia, Yang, Chen, Hongqi, Han, Huazhong, Yang, Yongzhi, Wu, Wen, Gao, Renyuan, Qin, Huanlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691313/
https://www.ncbi.nlm.nih.gov/pubmed/23826144
http://dx.doi.org/10.1371/journal.pone.0066814