Abnormal Ca(2+) homeostasis, atrial arrhythmogenesis, and sinus node dysfunction in murine hearts modeling RyR2 modification

Ryanodine receptor type 2 (RyR2) mutations are implicated in catecholaminergic polymorphic ventricular tachycardia (CPVT) thought to result from altered myocyte Ca(2+) homeostasis reflecting inappropriate “leakiness” of RyR2-Ca(2+) release channels arising from increases in their basal activity, alt...

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Detalles Bibliográficos
Autores principales: Zhang, Yanmin, Matthews, Gareth D. K., Lei, Ming, Huang, Christopher L.-H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691467/
https://www.ncbi.nlm.nih.gov/pubmed/23805105
http://dx.doi.org/10.3389/fphys.2013.00150

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691467/
https://www.ncbi.nlm.nih.gov/pubmed/23805105
http://dx.doi.org/10.3389/fphys.2013.00150

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