Inhibition of a novel specific neuroglial integrin signaling pathway increases STAT3-mediated CNTF expression

BACKGROUND: Ciliary neurotrophic factor (CNTF) expression is repressed in astrocytes by neuronal contact in the CNS and is rapidly induced by injury. Here, we defined an inhibitory integrin signaling pathway. RESULTS: The integrin substrates laminin, fibronectin and vitronectin, but not collagen, th...

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Detalles Bibliográficos
Autores principales: Keasey, Matthew P, Kang, Seong Su, Lovins, Chiharu, Hagg, Theo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691611/
https://www.ncbi.nlm.nih.gov/pubmed/23693126
http://dx.doi.org/10.1186/1478-811X-11-35

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691611/
https://www.ncbi.nlm.nih.gov/pubmed/23693126
http://dx.doi.org/10.1186/1478-811X-11-35

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