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Inhibition of a novel specific neuroglial integrin signaling pathway increases STAT3-mediated CNTF expression
BACKGROUND: Ciliary neurotrophic factor (CNTF) expression is repressed in astrocytes by neuronal contact in the CNS and is rapidly induced by injury. Here, we defined an inhibitory integrin signaling pathway. RESULTS: The integrin substrates laminin, fibronectin and vitronectin, but not collagen, th...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691611/ https://www.ncbi.nlm.nih.gov/pubmed/23693126 http://dx.doi.org/10.1186/1478-811X-11-35 |