Comparison of the effectiveness of antibody and cell-mediated immunity against inhaled and instilled influenza virus challenge

BACKGROUND: To evaluate immunity against influenza, mouse challenge studies are typically performed by intranasal instillation of a virus suspension to anesthetized animals. This results in an unnatural environment in the lower respiratory tract during infection, and therefore there is some concern...

Descripción completa

Detalles Bibliográficos
Autores principales: Rivers, Katie, Bowen, Larry E, Gao, Jin, Yang, Kevin, Trombley, John E, Bohannon, J Kyle, Eichelberger, Maryna C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691648/
https://www.ncbi.nlm.nih.gov/pubmed/23777453
http://dx.doi.org/10.1186/1743-422X-10-198

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691648/
https://www.ncbi.nlm.nih.gov/pubmed/23777453
http://dx.doi.org/10.1186/1743-422X-10-198

Ejemplares similares