Cargando…
Time-dependent changes in gene expression induced by secreted amyloid precursor protein-alpha in the rat hippocampus
BACKGROUND: Differential processing of the amyloid precursor protein liberates either amyloid-ß, a causative agent of Alzheimer’s disease, or secreted amyloid precursor protein-alpha (sAPPα), which promotes neuroprotection, neurotrophism, neurogenesis and synaptic plasticity. The underlying molecula...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691674/ https://www.ncbi.nlm.nih.gov/pubmed/23742273 http://dx.doi.org/10.1186/1471-2164-14-376 |