Organometallic Iridium(III) Anticancer Complexes with New Mechanisms of Action: NCI-60 Screening, Mitochondrial Targeting, and Apoptosis

[Image: see text] Platinum complexes related to cisplatin, cis-[PtCl(2)(NH(3))(2)], are successful anticancer drugs; however, other transition metal complexes offer potential for combating cisplatin resistance, decreasing side effects, and widening the spectrum of activity. Organometallic half-sandw...

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Detalles Bibliográficos
Autores principales: Hearn, Jessica M., Romero-Canelón, Isolda, Qamar, Bushra, Liu, Zhe, Hands-Portman, Ian, Sadler, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2013
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691721/
https://www.ncbi.nlm.nih.gov/pubmed/23618382
http://dx.doi.org/10.1021/cb400070a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691721/
https://www.ncbi.nlm.nih.gov/pubmed/23618382
http://dx.doi.org/10.1021/cb400070a

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