Effect of amitriptyline on tetrodotoxin-resistant Na(v)1.9 currents in nociceptive trigeminal neurons

BACKGROUND: Amitriptyline (AMI) is tricyclic antidepressant that has been widely used to manage various chronic pains such as migraines. Its efficacy is attributed to its blockade of voltage-gated sodium channels (VGSCs). However, the effects of AMI on the tetrodotoxin-resistant (TTX-r) sodium chann...

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Detalles Bibliográficos
Autores principales: Liang, Jingyao, Liu, Xiaoyan, Zheng, Jianquan, Yu, Shengyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691845/
https://www.ncbi.nlm.nih.gov/pubmed/24228717
http://dx.doi.org/10.1186/1744-8069-9-31

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691845/
https://www.ncbi.nlm.nih.gov/pubmed/24228717
http://dx.doi.org/10.1186/1744-8069-9-31

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