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An LPA species (18:1 LPA) plays key roles in the self-amplification of spinal LPA production in the peripheral neuropathic pain model

BACKGROUND: We previously reported that nerve injury-induced neuropathic pain is initiated by newly produced lysophosphatidic acid (LPA). RESULTS: In this study, we developed a quantitative mass spectrometry for detecting LPA species by using Phos-tag. Following nerve injury, the levels of 18:1, 16:...

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Detalles Bibliográficos
Autores principales: Ma, Lin, Nagai, Jun, Chun, Jerold, Ueda, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691926/
https://www.ncbi.nlm.nih.gov/pubmed/23773289
http://dx.doi.org/10.1186/1744-8069-9-29