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Axonal neuregulin 1 is a rate limiting but not essential factor for nerve remyelination

Neuregulin 1 acts as an axonal signal that regulates multiple aspects of Schwann cell development including the survival and migration of Schwann cell precursors, the ensheathment of axons and subsequent elaboration of the myelin sheath. To examine the role of this factor in remyelination and repair...

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Detalles Bibliográficos
Autores principales: Fricker, Florence R., Antunes-Martins, Ana, Galino, Jorge, Paramsothy, Remi, La Russa, Federica, Perkins, James, Goldberg, Rebecca, Brelstaff, Jack, Zhu, Ning, McMahon, Stephen B., Orengo, Christine, Garratt, Alistair N., Birchmeier, Carmen, Bennett, David L. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3692042/
https://www.ncbi.nlm.nih.gov/pubmed/23801741
http://dx.doi.org/10.1093/brain/awt148