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Axonal neuregulin 1 is a rate limiting but not essential factor for nerve remyelination
Neuregulin 1 acts as an axonal signal that regulates multiple aspects of Schwann cell development including the survival and migration of Schwann cell precursors, the ensheathment of axons and subsequent elaboration of the myelin sheath. To examine the role of this factor in remyelination and repair...
Autores principales: | Fricker, Florence R., Antunes-Martins, Ana, Galino, Jorge, Paramsothy, Remi, La Russa, Federica, Perkins, James, Goldberg, Rebecca, Brelstaff, Jack, Zhu, Ning, McMahon, Stephen B., Orengo, Christine, Garratt, Alistair N., Birchmeier, Carmen, Bennett, David L. H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3692042/ https://www.ncbi.nlm.nih.gov/pubmed/23801741 http://dx.doi.org/10.1093/brain/awt148 |
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