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GWAS3D: detecting human regulatory variants by integrative analysis of genome-wide associations, chromosome interactions and histone modifications

Interpreting the genetic variants located in the regulatory regions, such as enhancers and promoters, is an indispensable step to understand molecular mechanism of complex traits. Recent studies show that genetic variants detected by genome-wide association study (GWAS) are significantly enriched in...

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Detalles Bibliográficos
Autores principales: Li, Mulin Jun, Wang, Lily Yan, Xia, Zhengyuan, Sham, Pak Chung, Wang, Junwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3692118/
https://www.ncbi.nlm.nih.gov/pubmed/23723249
http://dx.doi.org/10.1093/nar/gkt456