PhysBinder: improving the prediction of transcription factor binding sites by flexible inclusion of biophysical properties

The most important mechanism in the regulation of transcription is the binding of a transcription factor (TF) to a DNA sequence called the TF binding site (TFBS). Most binding sites are short and degenerate, which makes predictions based on their primary sequence alone somewhat unreliable. We presen...

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Detalles Bibliográficos
Autores principales: Broos, Stefan, Soete, Arne, Hooghe, Bart, Moran, Raymond, van Roy, Frans, De Bleser, Pieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3692127/
https://www.ncbi.nlm.nih.gov/pubmed/23620286
http://dx.doi.org/10.1093/nar/gkt288

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3692127/
https://www.ncbi.nlm.nih.gov/pubmed/23620286
http://dx.doi.org/10.1093/nar/gkt288

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