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PhysBinder: improving the prediction of transcription factor binding sites by flexible inclusion of biophysical properties
The most important mechanism in the regulation of transcription is the binding of a transcription factor (TF) to a DNA sequence called the TF binding site (TFBS). Most binding sites are short and degenerate, which makes predictions based on their primary sequence alone somewhat unreliable. We presen...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3692127/ https://www.ncbi.nlm.nih.gov/pubmed/23620286 http://dx.doi.org/10.1093/nar/gkt288 |