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SigniSite: Identification of residue-level genotype-phenotype correlations in protein multiple sequence alignments

Identifying which mutation(s) within a given genotype is responsible for an observable phenotype is important in many aspects of molecular biology. Here, we present SigniSite, an online application for subgroup-free residue-level genotype–phenotype correlation. In contrast to similar methods, SigniS...

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Detalles Bibliográficos
Autores principales: Jessen, Leon Eyrich, Hoof, Ilka, Lund, Ole, Nielsen, Morten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3692133/
https://www.ncbi.nlm.nih.gov/pubmed/23761454
http://dx.doi.org/10.1093/nar/gkt497