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Apoptosis status and proliferative activity in mucopolysaccharidosis type I mice tongue mucosa cells

BACKGROUND: Mucopolysaccharidosis type I (MPS I) is caused by a deficiency of alfa-iduronidase (IDUA), which leads to intralysosomal accumulation of glysosaminoglycans. Evidences point secondary events like oxidative stress on lysosomal storage diseases including MPS I. Patients with MPS I present a...

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Detalles Bibliográficos
Autores principales: Noguti, Juliana, Pereira, Vanessa Gonçalves, Guilheiro, Joice Marques, Martins, Ana Maria, D’Almeida, Vânia, Ribeiro, Daniel Araki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3692203/
https://www.ncbi.nlm.nih.gov/pubmed/23814565