Diabetes-Associated Dry Eye Syndrome in a New Humanized Transgenic Model of Type 1 Diabetes

PURPOSE: Patients with Type 1 Diabetes (T1D) are at high risk of developing lacrimal gland dysfunction. We have developed a new model of human T1D using double-transgenic mice carrying HLA-DQ8 diabetes-susceptibility haplotype instead of mouse MHC-class II and expressing the human beta cell autoanti...

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Detalles Bibliográficos
Autores principales: Imam, Shahnawaz, Elagin, Raya B., Jaume, Juan Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3692403/
https://www.ncbi.nlm.nih.gov/pubmed/23805032

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3692403/
https://www.ncbi.nlm.nih.gov/pubmed/23805032

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