Characterization of Two Second-Site Mutations Preventing Wild Type Protein Aggregation Caused by a Dominant Negative PMA1 Mutant

The correct biogenesis and localization of Pma1 at the plasma membrane is essential for yeast growth. A subset of PMA1 mutations behave as dominant negative because they produce aberrantly folded proteins that form protein aggregates, which in turn provoke the aggregation of the wild type protein. O...

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Detalles Bibliográficos
Autores principales: Eraso, Pilar, Portillo, Francisco, Mazón, María J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3692421/
https://www.ncbi.nlm.nih.gov/pubmed/23825623
http://dx.doi.org/10.1371/journal.pone.0067080

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3692421/
https://www.ncbi.nlm.nih.gov/pubmed/23825623
http://dx.doi.org/10.1371/journal.pone.0067080

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