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A New Type of Na(+)-Driven ATP Synthase Membrane Rotor with a Two-Carboxylate Ion-Coupling Motif

The anaerobic bacterium Fusobacterium nucleatum uses glutamate decarboxylation to generate a transmembrane gradient of Na(+). Here, we demonstrate that this ion-motive force is directly coupled to ATP synthesis, via an F(1)F(o)-ATP synthase with a novel Na(+) recognition motif, shared by other human...

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Detalles Bibliográficos
Autores principales: Schulz, Sarah, Iglesias-Cans, Marina, Krah, Alexander, Yildiz, Özkan, Leone, Vanessa, Matthies, Doreen, Cook, Gregory M., Faraldo-Gómez, José D., Meier, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3692424/
https://www.ncbi.nlm.nih.gov/pubmed/23824040
http://dx.doi.org/10.1371/journal.pbio.1001596