Selective Methylation of CpGs at Regulatory Binding Sites Controls NNAT Expression in Wilms Tumors

Aberrant expression of imprinted genes, such as those coding for the insulin-like growth factor 2 (IGF2) and neuronatin (NNAT), is a characteristic of a variety of embryonic neoplasms, including Wilms tumor (WT). In case of IGF2, it is generally accepted that loss of imprinting in a differentially m...

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Detalles Bibliográficos
Autores principales: Hubertus, Jochen, Zitzmann, Ferdinand, Trippel, Franziska, Müller-Höcker, Josef, Stehr, Maximilian, von Schweinitz, Dietrich, Kappler, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3692448/
https://www.ncbi.nlm.nih.gov/pubmed/23825673
http://dx.doi.org/10.1371/journal.pone.0067605

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3692448/
https://www.ncbi.nlm.nih.gov/pubmed/23825673
http://dx.doi.org/10.1371/journal.pone.0067605

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