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ALKBH1 Is Dispensable for Abasic Site Cleavage during Base Excision Repair and Class Switch Recombination

Potential roles of the abasic site lyase activity associated with AlkB homolog 1 (ALKBH1) were assessed by studies focusing on the two cellular processes that create abasic sites as intermediates: base excision repair and class switch recombination. Alkbh1(−/−) pups (lacking exon 3) were born at a l...

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Detalles Bibliográficos
Autores principales: Müller, Tina A., Yu, Kefei, Hausinger, Robert P., Meek, Katheryn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3692455/
https://www.ncbi.nlm.nih.gov/pubmed/23825659
http://dx.doi.org/10.1371/journal.pone.0067403