Capsid Serotype and Timing of Injection Determines AAV Transduction in the Neonatal Mice Brain

Adeno-associated virus (AAV) mediated gene expression is a powerful tool for gene therapy and preclinical studies. A comprehensive analysis of CNS cell type tropism, expression levels and biodistribution of different capsid serotypes has not yet been undertaken in neonatal rodents. Our previous stud...

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Detalles Bibliográficos
Autores principales: Chakrabarty, Paramita, Rosario, Awilda, Cruz, Pedro, Siemienski, Zoe, Ceballos-Diaz, Carolina, Crosby, Keith, Jansen, Karen, Borchelt, David R., Kim, Ji-Yoen, Jankowsky, Joanna L., Golde, Todd E., Levites, Yona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3692458/
https://www.ncbi.nlm.nih.gov/pubmed/23825679
http://dx.doi.org/10.1371/journal.pone.0067680

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3692458/
https://www.ncbi.nlm.nih.gov/pubmed/23825679
http://dx.doi.org/10.1371/journal.pone.0067680

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