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Evidence of Evolutionary Constraints That Influences the Sequence Composition and Diversity of Mitochondrial Matrix Targeting Signals

Mitochondrial targeting signals (MTSs) are responsible for trafficking nuclear encoded proteins to their final destination within mitochondria. These sequences are diverse, sharing little amino acid homology and vary significantly in length, and although the formation of a positively-charged amphiph...

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Detalles Bibliográficos
Autores principales: Doyle, Stephen R., Kasinadhuni, Naga R. P., Chan, Chee Kai, Grant, Warwick N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3692466/
https://www.ncbi.nlm.nih.gov/pubmed/23825690
http://dx.doi.org/10.1371/journal.pone.0067938