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Tissue-Specific 5′ Heterogeneity of PPARα Transcripts and Their Differential Regulation by Leptin

The genes encoding nuclear receptors comprise multiple 5′untranslated exons, which give rise to several transcripts encoding the same protein, allowing tissue-specific regulation of expression. Both human and mouse peroxisome proliferator activated receptor (PPAR) α genes have multiple promoters, al...

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Detalles Bibliográficos
Autores principales: Garratt, Emma S., Vickers, Mark H., Gluckman, Peter D., Hanson, Mark A., Burdge, Graham C., Lillycrop, Karen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3692471/
https://www.ncbi.nlm.nih.gov/pubmed/23825665
http://dx.doi.org/10.1371/journal.pone.0067483