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Tissue-Specific 5′ Heterogeneity of PPARα Transcripts and Their Differential Regulation by Leptin
The genes encoding nuclear receptors comprise multiple 5′untranslated exons, which give rise to several transcripts encoding the same protein, allowing tissue-specific regulation of expression. Both human and mouse peroxisome proliferator activated receptor (PPAR) α genes have multiple promoters, al...
Autores principales: | Garratt, Emma S., Vickers, Mark H., Gluckman, Peter D., Hanson, Mark A., Burdge, Graham C., Lillycrop, Karen A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3692471/ https://www.ncbi.nlm.nih.gov/pubmed/23825665 http://dx.doi.org/10.1371/journal.pone.0067483 |
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