Germinal Center B-Cells Resist Transformation by Kras Independently of Tumor Suppressor Arf

Activating mutations in Ras (N- and K-) are the most common point mutations found in patients with multiple myeloma (MM) and are associated with poor clinical outcome. We sought to directly examine the role of Ras activation in MM pathogenesis and used two different tissue-specific Cre recombinase m...

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Detalles Bibliográficos
Autores principales: Mullins, Chelsea D., Su, Mack Y., Hucthagowder, Vishwanathan, Chu, Liang, Lu, Lan, Kulkarni, Shashikant, Novack, Deborah, Vij, Ravi, Tomasson, Michael H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3692489/
https://www.ncbi.nlm.nih.gov/pubmed/23825691
http://dx.doi.org/10.1371/journal.pone.0067941

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3692489/
https://www.ncbi.nlm.nih.gov/pubmed/23825691
http://dx.doi.org/10.1371/journal.pone.0067941

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