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IL-6 Regulates Mcl-(1L) Expression through the JAK/PI3K/Akt/CREB Signaling Pathway in Hepatocytes: Implication of an Anti-Apoptotic Role during Liver Regeneration

AIMS: To investigate the role and the regulation of the long variant of myeloid cell leukemia-1 protein (Mcl-1(L)) during liver regeneration. BACKGROUND: Liver regeneration is an important phenomenon after liver injury. The rat partial hepatectomy (PH) model was used to characterize liver regenerati...

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Detalles Bibliográficos
Autores principales: Chou, Chia-Hung, Lai, Shuo-Lun, Chen, Chiung-Nien, Lee, Po-Huang, Peng, Fu-Chuo, Kuo, Min-Liang, Lai, Hong-Shiee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3692501/
https://www.ncbi.nlm.nih.gov/pubmed/23825534
http://dx.doi.org/10.1371/journal.pone.0066268