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A New In Vivo Screening Paradigm to Accelerate Antimalarial Drug Discovery

The emergence of resistance to available antimalarials requires the urgent development of new medicines. The recent disclosure of several thousand compounds active in vitro against the erythrocyte stage of Plasmodium falciparum has been a major breakthrough, though converting these hits into new med...

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Detalles Bibliográficos
Autores principales: Jiménez-Díaz, María Belén, Viera, Sara, Ibáñez, Javier, Mulet, Teresa, Magán-Marchal, Noemí, Garuti, Helen, Gómez, Vanessa, Cortés-Gil, Lorena, Martínez, Antonio, Ferrer, Santiago, Fraile, María Teresa, Calderón, Félix, Fernández, Esther, Shultz, Leonard D., Leroy, Didier, Wilson, David M., García-Bustos, José Francisco, Gamo, Francisco Javier, Angulo-Barturen, Iñigo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3692522/
https://www.ncbi.nlm.nih.gov/pubmed/23825598
http://dx.doi.org/10.1371/journal.pone.0066967