Cargando…

Plasmodium falciparum Erythrocytic Stage Parasites Require the Putative Autophagy Protein PfAtg7 for Normal Growth

Analysis of the Plasmodium falciparum genome reveals a limited number of putative autophagy genes, specifically the four genes involved in ATG8 lipidation, an essential step in formation of autophagosomes. In yeast, Atg8 lipidation requires the E1-type ligase Atg7, an E2-type ligase Atg3, and a cyst...

Descripción completa

Detalles Bibliográficos
Autores principales: Walker, Dawn M., Mahfooz, Najmus, Kemme, Katherine A., Patel, Viral C., Spangler, Maribeth, Drew, Mark E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3692556/
https://www.ncbi.nlm.nih.gov/pubmed/23825614
http://dx.doi.org/10.1371/journal.pone.0067047