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Plasmodium falciparum Erythrocytic Stage Parasites Require the Putative Autophagy Protein PfAtg7 for Normal Growth
Analysis of the Plasmodium falciparum genome reveals a limited number of putative autophagy genes, specifically the four genes involved in ATG8 lipidation, an essential step in formation of autophagosomes. In yeast, Atg8 lipidation requires the E1-type ligase Atg7, an E2-type ligase Atg3, and a cyst...
Autores principales: | Walker, Dawn M., Mahfooz, Najmus, Kemme, Katherine A., Patel, Viral C., Spangler, Maribeth, Drew, Mark E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3692556/ https://www.ncbi.nlm.nih.gov/pubmed/23825614 http://dx.doi.org/10.1371/journal.pone.0067047 |
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