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Possible pitfalls investigating cell death responses in genetically engineered mouse models and derived cell lines
Genetically engineered mouse models are frequently used to identify pathophysiological consequences of deregulated cell death. Targeting pro-apoptotic or anti-apoptotic proteins of the extrinsic or intrinsic apoptotic signalling cascade is state of the art since more than two decades. Such animal mo...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Academic Press
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3693039/ https://www.ncbi.nlm.nih.gov/pubmed/23454286 http://dx.doi.org/10.1016/j.ymeth.2013.02.012 |