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Receptor-Mediated Endocytosis and Brain Delivery of Therapeutic Biologics

Transport of macromolecules across the blood-brain-barrier (BBB) requires both specific and nonspecific interactions between macromolecules and proteins/receptors expressed on the luminal and/or the abluminal surfaces of the brain capillary endothelial cells. Endocytosis and transcytosis play import...

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Detalles Bibliográficos
Autores principales: Xiao, Guangqing, Gan, Liang-Shang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3693099/
https://www.ncbi.nlm.nih.gov/pubmed/23840214
http://dx.doi.org/10.1155/2013/703545